Neocarton-Your Reliable Pharmaceutical Cartoning Machine Manufacturer in China
Pharmaceutical cartoning machines pack different medicines and additional materials into the carton and seal them. This process is easy to generate cross-contamination and damage. Our custom pharmaceutical cartoning machines use a cantilever structure that meets GMP requirements and equip a high-precision visual inspection system and digital audit trail function, ensuring zero pollution and stable boxing during high-speed packaging.Â
The machine can handle various medicine packaging, including blisters, bottles, vials, cartridges, syringes or ampoules. It supports pre-glued cartons and flat cartons. According to your production layout and special requirements, we design and manufacture machines with different functions and integrate them into your production line. They are used in many kinds of preparations and small medical devices.
Product Selection
It pushes medicine when the conveyor belt pauses, ensuring accurate box feeding and avoiding jams, and is used for irregular packaging or multi-component packaging.
The feeding and conveying process operates synchronously, preventing the vibration caused by frequent start and stop, used for medicine with mass production to reduce single-piece cost.Â
Features of Pharmaceutical Cartoning Machine
The structure design and materials all conform to GMP Pharmaceutical Packaging Standards, completely avoiding cross-contamination.
The high-precision servo feeding system prevents the breakage of glass bottles and blister plates, protecting expensive medicines.
All production parameter adjustments can be traced back, ensuring the authenticity and non-modifiability of the data during production and avoiding compliance and legal disputes.
It can handle different packaging types, sizes, and materials, and completes the switch within 20 minutes, significantly enhancing the efficiency of the production line.
Strict Cross-contamination Control
As a pharmaceutical cartoning machine manufacturer, our drive system uses a fully enclosed design and lubricated bearings to avoid the metal dust polluting the cleanroom, thereby affecting medicines. The exhaust ports of pneumatic components equip high-efficiency filters, which prevent over 99.9% of oil mist, meeting the strict dust-free requirements of pharmaceutical companies for the production environment.
Multi-level Folding and Flattening Technology
Some medicine instructions are thick after being folded and easy to open the carton, causing poor sealing, which affects the packaging appearance and medicine quality. As a professional pharmaceutical cartoning machine manufacturer, we offer multi-level folding technology that can be folded up to 6 times at most. The secondary flattening eliminates the tension of the paper, ensuring both medicine and instructions can be packed into boxes smoothly without rebounding in the long term.Â
Project Case
Our continuous pharmaceutical cartoning machine increases production speed to 300 boxes per minute, completing large orders for oral preparations in the short term. The visual inspection system ensures the instructions and traceability codes are 100% matched.
Our Intermittent pharmaceutical cartoning machine pushes the vials when the conveyor line pauses. We use flexible clamping to reduce the breakage rate of fragile Westlin bottles to zero. The specification switching time is reduced to 30 minutes to maintain packing efficiency.
- Specification
| Packaging Speed | 80 – 260 boxes per minute |
| Size Range of Carton(Length x Width x Height) | L: 70-200, W: 20-100, H: 15-70 (mm) |
| Paper Requirements | 250 – 350 g/m² (white cardstock / grey cardstock) |
| Instruction Manual Folding | 1 – 6 |
| Operational Mode | Continuous, intermittent |
| Application Range | blisters, bottles, vials, cartridges, syringes or ampoules |
| Overall Machine Power | 5.5 kW / AC 380V / 50Hz |
| Machine Material | The contact parts of the product are all made of stainless steel 304/316L. |
| Control System | PLC + HMI touch screen |
| Security Detection | Automatic removal of missing or empty boxes, automatic shutdown in case of material blockage |
Flat Cartons: the lateral support force is weak during opening, so we use a rotary multi-head suction and top loading system to allow it to fall naturally by gravity. This reduces the impact to the side walls and avoids deformation.
Pre-bonded paper box: its side forms a natural lateral channel after being opened and materials will be loaded into the carton through the side loading system. This conforms to the characteristics of cartons and increases packing speed.
The end of our production line is equipped with carton weighing machines, variable data printing stations and tamper-proof labeling machines to check weight, labels, and tracking information. During operation of these machines, the visual inspection system can reject substandard cartons, ensuring your medicine packaging is 100% traceable and compliant with regulatory requirements.
We offer flexible sealing methods to meet the anti-counterfeiting and usage requirements of different medicines.
Plug-in type: it is convenient for users to open frequently, suitable for OTC or those with low requirements for tamper-proofing.
Hot melt adhesive bonding: it achieves a tight and permanent seal and ensures the safety of the drugs. It is used for high-value prescription drugs, antibiotics, vaccines, etc.
The combination of the two: it balances the opening convenience and security protection, suitable for biological products, export drugs, etc.
Our pharmaceutical cartoning machines use a rotary suction structure and multi-head servo feeding to open cartons forcibly when sucking the carton. Even a very thin carton can be opened stably.
For cartons with a smooth surface, we customize silicone suction nozzles to ensure there is no slippage under high speed. This significantly reduces consumption waste and maintains the production line to operate stably. Â
Considering the high construction and maintenance cost of the cleanroom, our pharmaceutical cartoning machine pays attention to the modular compact design. It saves about 20% to 30% floor space compared with traditional machine models. You can choose different layouts based on your workshop condition to maximize production capacity within the limited space.
We offer remote diagnosis services. When your packaging machine malfunctions, our engineers can diagnose the PLC program through the cloud within 2 hours, solving 80% of the parameter adjustment issues within 4 hours and saving you the cost of expensive on-site maintenance.
Why Are Compliance and Hygiene Requirements so Important for Pharmaceutical Cartoning Machines?
Ensure The Safety and Efficacy of The Medicine
FDA and EMA formulate strict regulations on medicine packaging to ensure the safety and effectiveness. The GMP compliance requirements specify the operation logic and Fail-safe Rejection of the pharmaceutical packaging machine.
The pharmaceutical cartoning machine directly contacts the inner packaging of the product. The hygiene requirements for the machine protect medicine from pollution.
Shorten The Procurement Cycle
If your pharmaceutical cartoning machines meet the standards of the FDA and EMA, your machines have the qualifications to enter the global high-end market and can strive for a premium price.
For large pharmaceutical companies, a comprehensive compliance report demonstrates the low risk of the equipment, which can shorten the time for procurement decisions.
How Does Our Pharmaceutical Cartoning Machine Meet Compliance Requirements?
Hardware Compliance
Frame Material
Our cartoning machines use materials meeting specific quality and purity standards. Parts directly contacting the medicine use 304/316L stainless steel or pharmaceutical-grade materials, ensuring corrosion resistance without shedding.
Cantilevered Design
The design of our machines minimizes product contamination and maintains sterility. The traditional cartoning machine is located under the packaging area, which is prone to leaking lubricating oil and contaminating medicine. Our cantilevered design separates the transmission system and packaging area, preventing the medicine from being contaminated by lubricating oil and particles.
Software Compliance
Audit Trial
The audit trail records all the operation details of the pharmaceutical cartoning machine. When packaging quality problems occur, the regulatory agency can inspect the production process through an audit trail. Our pharmaceutical cartoning machine equips an audit trail module to ensure all the production data can be traced through the entire life cycle, helping you easily handle the inspections.
Multi-level Permission Management
Multi-level permission management sets operation permissions of different levels for operators, technicians, administrators, etc., allowing each parameter modification to locate an individual. This prevents operators from adjusting parameters without authorization, ensuring the authenticity and reliability of the data and helping you avoid compliance risks.
Environmental Control
GMP stipulates that the cartoning machine must operate in a clean and temperature-controlled environment. In practical applications, workshops of different pharmaceutical factories have different levels of cleanliness, and environments and weather also affect.
Our pharmaceutical cartoning machine uses a fully enclosed electrical cabinet and is equipped with a temperature and humidity adjustment device, enabling the machine to operate stably in the D-level to B-level cleanrooms.
Inspection System
Code Inspection
The high-precision visual inspection system scans the codes and instructions on the carton in real time. Once any errors are detected, the system will automatically eliminate them and record the confirmation.
Integrity Detection
The integrity detection inspects if the contents of the carton are missing or the sealing is tight. The production line will remove the non-conforming products. This ensures each medicine has complete materials, avoiding quality accidents.
How Does Our Pharmaceutical Cartoning Machine Meet Hygiene Requirements?
Sanitary Grade Material
High grade 304/316L stainless steel can resist the corrosion of frequent disinfection from alcohol, hydrogen peroxide or acid-base cleaners, without generating oxides. It has stable chemical properties and does not release metal ions, ensuring the chemical purity of the medicine.
Our sanitary-grade pharmaceutical cartoning machine undergoes polishing treatment and achieves a surface roughness of Ra ≤ 0.8μm. This prevents bacteria and dust particles from adhering to the surface and avoids the impact of cross-contamination on your products.
Easy-to-clean Structure
Our stainless steel cartoning machines use overall bending without weld seams or grooves, avoiding bacteria and particles residing. The inclination angle of the surface is ≥3°, and water can flow away without accumulation. The CIP cleaning can cover all surfaces contacting the product, achieving thorough cleaning
High Sealing Performance
The machine ensures the medicine is fully sealed, protecting it from being affected by external dust, microorganisms, or dirt during transportation. Some medicines are sensitive to humidity, and high sealing performance prevents them from getting damp and ensures their quality throughout their entire life cycle.
How to Choose The Suitable Pharmaceutical Cartoning Machine?
Product Feature
If your product is of a single variety and mass production, we recommend a continuous pharmaceutical cartoning machine. It maintains stability in high-speed operation, and the huge annual output helps you minimize the cost of single packaging.
If your product is fragile and has various specifications, we recommend an intermittent pharmaceutical cartoning machine. It grasps precisely and has a smaller impact force on fragile materials.
Production Line Requirements
If your equipment will add new modules in the future or be connected to downstream machines, we recommend machines that reserve room for upgrading. Machines without reserved interfaces need huge renovation costs for later connection.
Our cartoning machines reserve mechanical synchronous shaft interfaces and digital interfaces, and can be plugged in when adding equipment, avoiding the economic loss caused by suspended production.
Specification Switching Time
Specification switching is a key factor that affects production efficiency. A long switching time leads to a long downtime.
We suggest choosing machines that achieve quick and tool-free switching first, which shortens the switching time within 20 minutes and allows your production line to handle more small orders.
